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RAC1 antibody

Product Specifications

Background

RAC1b, also named as TC25, belongs to the small GTPase superfamily and Rho family. RAC1 is a plasma membrane-associated small GTPase which cycles between active GTP-bound and inactive GDP-bound states. In its active state, it binds to a variety of effector proteins to regulate cellular responses such as secretory processes, phagocytosis of apoptotic cells, epithelial cell polarization and growth-factor induced formation of membrane ruffles.

Synonyms

Ras-related C3 botulinum toxin substrate 1|Cell migration-inducing gene 5 protein|Ras-like protein TC25|p21-Rac1|RAC1|TC25

Gene ID

5879

UniProt

P63000

Host

Mouse

Reactivity

Human, Mouse, Rat

Immunogen

Ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)

Target

RAC1

Clonality

Monoclonal

Isotype

IgG1

Applications

ELISA, WB,IHC, IP,IF

Field of Research

Immunology, Cardiovascular, Signal Transduction

Purification

Protein A+G purification

Dilution

WB: 1:1000-1:4000; IP: 1:200-1:2000; IHC: 1:50-1:500; IF: 1:50-1:500

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Molecular Weight

21 kDa

Shipping Conditions

4°C with ice bag

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Clone ID

5D9

Tested Applications

ELISA, WB, IHC, IP, IF

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