Cornuside (Standard)
Product Specifications
UNSPSC Description
Cornuside (Standard) is the analytical standard of Cornuside. This product is intended for research and analytical applications. Cornuside is a secoiridoid glucoside isolated from the fruit of Cornus officinalis Sieb. et Zucc., which is a traditional oriental medicine for treating inflammatory diseases and invigorating blood circulation. Cornuside inhibits mast cell-mediated allergic response by down-regulating MAPK and NF-κB signaling pathways. Cornuside has anti-allergic effects in vivo and in vitro which suggests a therapeutic application of this agent in inflammatory allergic diseases[1].
Target Antigen
NF-κB; p38 MAPK
Type
Reference Standards
Related Pathways
MAPK/ERK Pathway;NF-κB
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/cornuside-standard.html
Smiles
O=C(C1=CC(O)=C(O)C(O)=C1)OCCC(C(C(OC)=O)=COC2OC(C(C(O)C3O)O)OC3CO)C2C=C
Molecular Weight
542.49
References & Citations
[1]Li L, et al. Cornuside inhibits mast cell-mediated allergic response by down-regulating MAPK and NF-κB signaling pathways. Biochem Biophys Res Commun. 2016 Apr 29;473(2):408-14.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-N0631R/Cornuside-Standard-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-N0631R/
CAS Number
131189-57-6
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