RAB3GAP2 antibody
Product Specifications
Background
Regulatory subunit of a GTPase activating protein that has specificity for Rab3 subfamily(RAB3A, RAB3B, RAB3C and RAB3D). Rab3 proteins are involved in regulated exocytosis of neurotransmitters and hormones. Rab3 GTPase-activating complex specifically converts active Rab3-GTP to the inactive form Rab3-GDP. Required for normal eye and brain development. May participate in neurodevelopmental processes such as proliferation, migration and differentiation before synapse formation, and non-synaptic vesicular release of neurotransmitters.
Synonyms
Rab3 GTPase-activating protein non-catalytic subunit|RGAP-iso|Rab3 GTPase-activating protein 150 kDa subunit|Rab3-GAP p150 (Rab3-GAP150)|Rab3-GAP regulatory subunit|RAB3GAP2|KIAA0839
Gene ID
25782
UniProt
Q9H2M9
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
RAB3 GTPase activating protein subunit 2(non-catalytic)
Target
RAB3GAP2
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Field of Research
Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IHC: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
110/130/150 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)
CAS Number
9007-83-4
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