RAB3GAP1 antibody
Product Specifications
Background
Probable catalytic subunit of a GTPase activating protein that has specificity for Rab3 subfamily (RAB3A, RAB3B, RAB3C and RAB3D) . Rab3 proteins are involved in regulated exocytosis of neurotransmitters and hormones. Specifically converts active Rab3-GTP to the inactive form Rab3-GDP. Required for normal eye and brain development. May participate in neurodevelopmental processes such as proliferation, migration and differentiation before synapse formation, and non-synaptic vesicular release of neurotransmitters.
Synonyms
Rab3 GTPase-activating protein catalytic subunit|RAB3 GTPase-activating protein 130 kDa subunit|Rab3-GAP p130 (Rab3-GAP) |RAB3GAP1|KIAA0066|RAB3GAP
Gene ID
22930
UniProt
Q15042
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
RAB3 GTPase activating protein subunit 1 (catalytic)
Target
RAB3GAP1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC, IF, IP
Field of Research
Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200; IF: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
130 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC, IF, IP
Immunogen Sequence
500-800aa
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