RAB3GAP1 antibody
Product Specifications
Background
Probable catalytic subunit of a GTPase activating protein that has specificity for Rab3 subfamily(RAB3A, RAB3B, RAB3C and RAB3D). Rab3 proteins are involved in regulated exocytosis of neurotransmitters and hormones. Specifically converts active Rab3-GTP to the inactive form Rab3-GDP. Required for normal eye and brain development. May participate in neurodevelopmental processes such as proliferation, migration and differentiation before synapse formation, and non-synaptic vesicular release of neurotransmitters.
Synonyms
Rab3 GTPase-activating protein catalytic subunit|RAB3 GTPase-activating protein 130 kDa subunit|Rab3-GAP p130 (Rab3-GAP)|RAB3GAP1|KIAA0066|RAB3GAP
Gene ID
22930
UniProt
Q15042
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
RAB3 GTPase activating protein subunit 1(catalytic)
Target
RAB3GAP1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC, IF, IP
Field of Research
Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200; IF: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
130 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)
CAS Number
9007-83-4
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