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RAB38 antibody

Product Specifications

Background

May be involved in melanosomal transport and docking. Involved in the proper sorting of TYRP1. Involved in peripheral melanosomal distribution of TYRP1 in melanocytes; the function, which probably is implicating vesicle-trafficking, includes cooperation with ANKRD27 and VAMP7 (By similarity) . Plays a role in the maturation of phagosomes that engulf pathogens, such as S.aureus and M.tuberculosis (PubMed:21255211) . Plays an important role in the control of melanin production and melanosome biogenesis (PubMed:23084991) . In concert with RAB32, regulates the proper trafficking of melanogenic enzymes TYR, TYRP1 and DCT/TYRP2 to melanosomes in melanocytes (By similarity) .

Synonyms

Ras-related protein Rab-38|Melanoma antigen NY-MEL-1|RAB38

Gene ID

23682

UniProt

P57729

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

RAB38, member RAS oncogene family

Target

RAB38

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, WB

Field of Research

Signal Transduction

Purification

Immunogen affinity purified

Dilution

WB: 1:500-1:2000

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Molecular Weight

25 kDa

Shipping Conditions

4°C with ice bag

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Tested Applications

ELISA, WB

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