RAB11FIP2 antibody
Product Specifications
Background
A Rab11 effector binding preferentially phosphatidylinositol 3,4,5-trisphosphate (PtdInsP3) and phosphatidic acid (PA) and acting in the regulation of the transport of vesicles from the endosomal recycling compartment (ERC) to the plasma membrane. Involved in insulin granule exocytosis. Also involved in receptor-mediated endocytosis and membrane trafficking of recycling endosomes, probably originating from clathrin-coated vesicles. Required in a complex with MYO5B and RAB11 for the transport of NPC1L1 to the plasma membrane. Also acts as a regulator of cell polarity.
Synonyms
Rab11 family-interacting protein 2 (Rab11-FIP2) |NRip11|RAB11FIP2|KIAA0941
Gene ID
22841
UniProt
Q7L804
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
RAB11 family interacting protein 2 (class I)
Target
RAB11FIP2
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IF
Field of Research
Signal Transduction
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IF: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
58 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IF
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