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PYCR2 antibody

Product Specifications

Background

Housekeeping enzyme that catalyzes the last step in proline biosynthesis. In some cell types, such as erythrocytes, its primary function may be the generation of NADP (+) . Can utilize both NAD and NADP. Has higher affinity for NADP, but higher catalytic efficiency with NADH (PubMed:2722838, PubMed:6894153) . Involved in cellular response to oxidative stress (PubMed:25865492) .

Synonyms

Pyrroline-5-carboxylate reductase 2 (P5C reductase 2, P5CR 2) |PYCR2

Gene ID

29920

UniProt

Q96C36

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Pyrroline-5-carboxylate reductase family, member 2

Target

PYCR2

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, WB, IHC, IF, IP

Field of Research

Metabolism

Purification

Immunogen affinity purified

Dilution

WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200; IF: 1:20-1:200

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Molecular Weight

34 kDa

Shipping Conditions

4°C with ice bag

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Tested Applications

ELISA, WB, IHC, IF, IP

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