PYCR2 antibody
Product Specifications
Background
Housekeeping enzyme that catalyzes the last step in proline biosynthesis. In some cell types, such as erythrocytes, its primary function may be the generation of NADP (+) . Can utilize both NAD and NADP. Has higher affinity for NADP, but higher catalytic efficiency with NADH (PubMed:2722838, PubMed:6894153) . Involved in cellular response to oxidative stress (PubMed:25865492) .
Synonyms
Pyrroline-5-carboxylate reductase 2 (P5C reductase 2, P5CR 2) |PYCR2
Gene ID
29920
UniProt
Q96C36
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Pyrroline-5-carboxylate reductase family, member 2
Target
PYCR2
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC, IF, IP
Field of Research
Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200; IF: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
34 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC, IF, IP
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