PUF60 antibody
Product Specifications
Background
This gene encodes a nucleic acid-binding protein that plays a role in a variety of nuclear processes, including pre-mRNA splicing and transcriptional regulation. The encoded protein forms a complex with the far upstream DNA element (FUSE) and FUSE-binding protein at the myelocytomatosis oncogene (MYC) promoter. This complex represses MYC transcription through the core-TFIIH basal transcription factor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Synonyms
Poly (U) -binding-splicing factor PUF60|60 kDa poly (U) -binding-splicing factor|FUSE-binding protein-interacting repressor (FBP-interacting repressor) |Ro-binding protein 1 (RoBP1) |Siah-binding protein 1 (Siah-BP1) |PUF60|FIR|ROBPI|SIAHBP1
Gene ID
22827
UniProt
Q9UHX1
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Poly-U binding splicing factor 60KDa
Target
PUF60
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC, IF, IP
Field of Research
Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:100; IP: 1:20 - 1:50
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
65 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC, IF, IP
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
VD12N547 1 Each
Mouse Anti-Canine Tubulin Beta 3 Chain (TUBB3) Monoclonal Antibody-[HRP]
Ask
View Details 
MBS6200937-01 0.1 mL
GABRA3 (Gamma-aminobutyric Acid Receptor Subunit alpha-3, GABA(A) Receptor Subunit alpha-3) (MaxLight 490)
Ask
View Details 
MBS6200937-02 5x 0.1 mL
GABRA3 (Gamma-aminobutyric Acid Receptor Subunit alpha-3, GABA(A) Receptor Subunit alpha-3) (MaxLight 490)
Ask
View Details