PTPRZ1 antibody
Product Specifications
Background
Protein tyrosine phosphatase that negatively regulates oligodendrocyte precursor proliferation in the embryonic spinal cord. Required for normal differentiation of the precursor cells into mature, fully myelinating oligodendrocytes. May play a role in protecting oligondendrocytes against apoptosis. May play a role in the establishment of contextual memory, probably via the dephosphorylation of proteins that are part of important signaling cascades(By similarity).
Synonyms
Receptor-type tyrosine-protein phosphatase zeta (R-PTP-zeta)|Protein-tyrosine phosphatase receptor type Z polypeptide 1|Protein-tyrosine phosphatase receptor type Z polypeptide 2|R-PTP-zeta-2|PTPRZ1|HTPZP2|PTPRZ|PTPRZ2|PTPZ
Gene ID
5803
UniProt
P23471
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
protein tyrosine phosphatase, receptor-type, Z polypeptide 1
Target
PTPRZ1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB
Field of Research
Signal Transduction, Metabolism, Developmental biology
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
163-175 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)
CAS Number
9007-83-4
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