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PTPRZ1 antibody

Product Specifications

Background

Protein tyrosine phosphatase that negatively regulates oligodendrocyte precursor proliferation in the embryonic spinal cord. Required for normal differentiation of the precursor cells into mature, fully myelinating oligodendrocytes. May play a role in protecting oligondendrocytes against apoptosis. May play a role in the establishment of contextual memory, probably via the dephosphorylation of proteins that are part of important signaling cascades (By similarity) .

Synonyms

Receptor-type tyrosine-protein phosphatase zeta (R-PTP-zeta) |Protein-tyrosine phosphatase receptor type Z polypeptide 1|Protein-tyrosine phosphatase receptor type Z polypeptide 2|R-PTP-zeta-2|PTPRZ1|HTPZP2|PTPRZ|PTPRZ2|PTPZ

Gene ID

5803

UniProt

P23471

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Protein tyrosine phosphatase, receptor-type, Z polypeptide 1

Target

PTPRZ1

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, WB

Field of Research

Signal Transduction, Metabolism, Developmental biology

Purification

Immunogen affinity purified

Dilution

WB: 1:500-1:2000

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Molecular Weight

163-175 kDa

Shipping Conditions

4°C with ice bag

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Tested Applications

ELISA, WB

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