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PTPN23 antibody

Product Specifications

Background

Plays a role in sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs) via its interaction with the ESCRT-I complex (endosomal sorting complex required for transport I), and possibly also other ESCRT complexes. May act as a negative regulator of Ras-mediated mitogenic activity. Plays a role in ciliogenesis.

Synonyms

Tyrosine-protein phosphatase non-receptor type 23|His domain-containing protein tyrosine phosphatase (HD-PTP) |Protein tyrosine phosphatase TD14 (PTP-TD14) |PTPN23|KIAA1471

Gene ID

25930

UniProt

Q9H3S7

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Protein tyrosine phosphatase, non-receptor type 23

Target

PTPN23

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, WB, IHC, IP

Field of Research

Signal Transduction, Metabolism

Purification

Immunogen affinity purified

Dilution

WB: 1:500-1:5000; IP: 1:200-1:2000; IHC: 1:100-1:400; IF: 1:50-1:500

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Molecular Weight

179 kDa

Shipping Conditions

4°C with ice bag

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Tested Applications

ELISA, WB, IHC, IP

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