PTPN23 antibody
Product Specifications
Background
Plays a role in sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs) via its interaction with the ESCRT-I complex (endosomal sorting complex required for transport I), and possibly also other ESCRT complexes. May act as a negative regulator of Ras-mediated mitogenic activity. Plays a role in ciliogenesis.
Synonyms
Tyrosine-protein phosphatase non-receptor type 23|His domain-containing protein tyrosine phosphatase (HD-PTP) |Protein tyrosine phosphatase TD14 (PTP-TD14) |PTPN23|KIAA1471
Gene ID
25930
UniProt
Q9H3S7
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Protein tyrosine phosphatase, non-receptor type 23
Target
PTPN23
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC, IP
Field of Research
Signal Transduction, Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:5000; IP: 1:200-1:2000; IHC: 1:100-1:400; IF: 1:50-1:500
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
179 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC, IP
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