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PTPN14 antibody

Product Specifications

Background

Protein tyrosine phosphatase which may play a role in the regulation of lymphangiogenesis, cell-cell adhesion, cell-matrix adhesion, cell migration, cell growth and also regulates TGF-beta gene expression, thereby modulating epithelial-mesenchymal transition. Mediates beta-catenin dephosphorylation at adhesion junctions. Acts as a negative regulator of the oncogenic property of YAP, a downstream target of the hippo pathway, in a cell density-dependent manner. May function as a tumor suppressor.

Synonyms

Tyrosine-protein phosphatase non-receptor type 14|Protein-tyrosine phosphatase pez|PTPN14|PEZ|PTPD2

Gene ID

5784

UniProt

Q15678

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Protein tyrosine phosphatase, non-receptor type 14

Target

PTPN14

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, WB, IHC

Field of Research

Metabolism, Developmental biology

Purification

Immunogen affinity purified

Dilution

WB: 1:200-1:2000; IHC: 1:20-1:200

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Molecular Weight

150 kDa

Shipping Conditions

4°C with ice bag

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Tested Applications

ELISA, WB, IHC

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