PTBP2 antibody
Product Specifications
Background
RNA-binding protein which binds to intronic polypyrimidine tracts and mediates negative regulation of exons splicing. May antagonize in a tissue-specific manner the ability of NOVA1 to activate exon selection. In addition to its function in pre-mRNA splicing, plays also a role in the regulation of translation. Isoform 5 has a reduced affinity for RNA.
Synonyms
Polypyrimidine tract-binding protein 2|Neural polypyrimidine tract-binding protein|Neurally-enriched homolog of PTB|PTB-like protein|PTBP2|NPTB|PTB|PTBLP
Gene ID
58155
UniProt
Q9UKA9
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Polypyrimidine tract binding protein 2
Target
PTBP2
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB
Field of Research
Neuroscience, Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
57-60 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB
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