PRDX1 antibody
Product Specifications
Background
Involved in redox regulation of the cell. Reduces peroxides with reducing equivalents provided through the thioredoxin system but not from glutaredoxin. May play an important role in eliminating peroxides generated during metabolism. Might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H(2)O(2). Reduces an intramolecular disulfide bond in GDPD5 that gates the ability to GDPD5 to drive postmitotic motor neuron differentiation(By similarity).
Synonyms
Peroxiredoxin-1|Natural killer cell-enhancing factor A (NKEF-A)|Proliferation-associated gene protein (PAG)|Thioredoxin peroxidase 2|Thioredoxin-dependent peroxide reductase 2|Thioredoxin-dependent peroxiredoxin 1|PRDX1|PAGA|PAGB|TDPX2
Gene ID
5052
UniProt
Q06830
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
peroxiredoxin 1
Target
PRDX1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IF
Field of Research
Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IF: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
23 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)
CAS Number
9007-83-4
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