PPP6C antibody
Product Specifications
Background
Catalytic subunit of protein phosphatase 6 (PP6) . PP6 is a component of a signaling pathway regulating cell cycle progression in response to IL2 receptor stimulation. N-terminal domain restricts G1 to S phase progression in cancer cells, in part through control of cyclin D1. Downregulates MAP3K7 kinase activation of the IL1 signaling pathway by dephosphorylation of MAP3K7.
Synonyms
Serine/threonine-protein phosphatase 6 catalytic subunit (PP6C) |Serine/threonine-protein phosphatase 6 catalytic subunit, N-terminally processed|PPP6C|PPP6
Gene ID
5537
UniProt
O00743
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Protein phosphatase 6, catalytic subunit
Target
PPP6C
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB
Field of Research
Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
35 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB
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