PPP2R2B antibody
Product Specifications
Background
The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. Within the PP2A holoenzyme complex, isoform 2 is required to promote proapoptotic activity (By similarity) . Isoform 2 regulates neuronal survival through the mitochondrial fission and fusion balance (By similarity) .
Synonyms
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform|PP2A subunit B isoform B55-beta|PP2A subunit B isoform PR55-beta|PP2A subunit B isoform R2-beta|PP2A subunit B isoform beta|PPP2R2B
Gene ID
5521
UniProt
Q00005
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Protein phosphatase 2 (formerly 2A), regulatory subunit B, beta isoform
Target
PPP2R2B
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IF, IP
Field of Research
Neuroscience, Signal Transduction, Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:1000; IP: 1:500-1:1000; IF: 1:10-1:100
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
52 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IF, IP
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