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PPP1R13L antibody

Product Specifications

Background

Regulator that plays a central role in regulation of apoptosis and transcription via its interaction with NF-kappa-B and p53/TP53 proteins. Blocks transcription of HIV-1 virus by inhibiting the action of both NF-kappa-B and SP1. Also inhibits p53/TP53 function, possibly by preventing the association between p53/TP53 and ASPP1 or ASPP2, and therefore suppressing the subsequent activation of apoptosis.

Synonyms

RelA-associated inhibitor|Inhibitor of ASPP protein (Protein iASPP) |NFkB-interacting protein 1|PPP1R13B-like protein|PPP1R13L|IASPP|NKIP1|PPP1R13BL|RAI

Gene ID

10848

UniProt

Q8WUF5

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

Protein phosphatase 1, regulatory (inhibitor) subunit 13 like

Target

PPP1R13L

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, WB, IHC

Field of Research

Cell Division and Proliferation, Metabolism

Purification

Immunogen affinity purified

Dilution

WB: 1:500-1:2000; IHC: 1:20-1:200

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Molecular Weight

110 kDa

Shipping Conditions

4°C with ice bag

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Tested Applications

ELISA, WB, IHC

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