PPP1R13L antibody
Product Specifications
Background
Regulator that plays a central role in regulation of apoptosis and transcription via its interaction with NF-kappa-B and p53/TP53 proteins. Blocks transcription of HIV-1 virus by inhibiting the action of both NF-kappa-B and SP1. Also inhibits p53/TP53 function, possibly by preventing the association between p53/TP53 and ASPP1 or ASPP2, and therefore suppressing the subsequent activation of apoptosis.
Synonyms
RelA-associated inhibitor|Inhibitor of ASPP protein (Protein iASPP) |NFkB-interacting protein 1|PPP1R13B-like protein|PPP1R13L|IASPP|NKIP1|PPP1R13BL|RAI
Gene ID
10848
UniProt
Q8WUF5
Host
Rabbit
Reactivity
Human, Rat, Mouse
Immunogen
Protein phosphatase 1, regulatory (inhibitor) subunit 13 like
Target
PPP1R13L
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, IHC, IF, IP, WB
Field of Research
Cell Division and Proliferation, Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200; IF: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
110 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, IHC, IF, IP, WB
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