PPIL2 antibody
Product Specifications
Background
May catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides thereby assisting the folding of proteins(By similarity). May also function as a chaperone, playing a role in transport to the cell membrane of BSG for instance(PubMed:15946952). May also have a protein ubiquitin ligase activity acting as an E3 ubiquitin protein ligase or as an ubiquitin-ubiquitin ligase promoting elongation of ubiquitin chains on substrates. By mediating 'Lys-48'-linked polyubiquitination of proteins could target them for proteasomal degradation(PubMed:11435423).
Synonyms
RING-type E3 ubiquitin-protein ligase PPIL2|CYC4|Cyclophilin-60 (Cyclophilin-like protein Cyp-60, Cyp60, hCyP-60)|Probable inactive peptidyl-prolyl cis-trans isomerase-like 2 (PPIase)|Rotamase PPIL2|PPIL2
Gene ID
23759
UniProt
Q13356
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
peptidylprolyl isomerase(cyclophilin)-like 2
Target
PPIL2
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB
Field of Research
Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
59 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)
CAS Number
9007-83-4
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