PPARG antibody
Product Specifications
Background
This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) subfamily of nuclear receptors. PPARs form heterodimers with retinoid X receptors (RXRs) and these heterodimers regulate transcription of various genes. Three subtypes of PPARs are known: PPAR-alpha, PPAR-delta, and PPAR-gamma. The protein encoded by this gene is PPAR-gamma and is a regulator of adipocyte differentiation. Additionally, PPAR-gamma has been implicated in the pathology of numerous diseases including obesity, diabetes, atherosclerosis and cancer. Alternatively spliced transcript variants that encode different isoforms have been described.
Synonyms
Peroxisome proliferator-activated receptor gamma (PPAR-gamma) |Nuclear receptor subfamily 1 group C member 3|PPARG|NR1C3
Gene ID
5468
UniProt
P37231
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Peroxisome proliferator-activated receptor gamma
Target
PPARG
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IF, IHC, IP
Field of Research
Signal Transduction, Metabolism, Cardiovascular, Developmental biology, Neuroscience, Stem Cells
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IHC: 1:50-1:200; IF: 1:10-1:100; IP: 1:500-1:1000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
58 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IF, IHC, IP
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