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POLR2C antibody

Product Specifications

Background

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB3 is part of the core element with the central large cleft and the clamp element that moves to open and close the cleft (By similarity) .

Synonyms

DNA-directed RNA polymerase II subunit RPB3 (RNA polymerase II subunit 3, RNA polymerase II subunit B3) |DNA-directed RNA polymerase II 33 kDa polypeptide (RPB33) |DNA-directed RNA polymerase II subunit C|RPB31|POLR2C

Gene ID

5432

UniProt

P19387

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Polymerase (RNA) II (DNA directed) polypeptide C, 33kDa

Target

POLR2C

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, WB, IHC, IP

Field of Research

Epigenetics, Metabolism

Purification

Immunogen affinity purified

Dilution

WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Molecular Weight

33 kDa

Shipping Conditions

4°C with ice bag

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Tested Applications

ELISA, WB, IHC, IP

Frequently Asked Questions

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