POLR2C antibody
Product Specifications
Background
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB3 is part of the core element with the central large cleft and the clamp element that moves to open and close the cleft (By similarity) .
Synonyms
DNA-directed RNA polymerase II subunit RPB3 (RNA polymerase II subunit 3, RNA polymerase II subunit B3) |DNA-directed RNA polymerase II 33 kDa polypeptide (RPB33) |DNA-directed RNA polymerase II subunit C|RPB31|POLR2C
Gene ID
5432
UniProt
P19387
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Polymerase (RNA) II (DNA directed) polypeptide C, 33kDa
Target
POLR2C
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC, IP
Field of Research
Epigenetics, Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
33 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC, IP
Frequently Asked Questions
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