PLSCR1 antibody
Product Specifications
Background
May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. May play a central role in the initiation of fibrin clot formation, in the activation of mast cells and in the recognition of apoptotic and injured cells by the reticuloendothelial system. May play a role in the antiviral response of interferon (IFN) by amplifying and enhancing the IFN response through increased expression of select subset of potent antiviral genes. May contribute to cytokine-regulated cell proliferation and differentiation.
Synonyms
Phospholipid scramblase 1 (PL scramblase 1) |Ca (2+) -dependent phospholipid scramblase 1|Erythrocyte phospholipid scramblase|Mg (2+) -dependent nuclease|MmTRA1b|PLSCR1
Gene ID
5359
UniProt
O15162
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Phospholipid scramblase 1
Target
PLSCR1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC, FC, IF, IP
Field of Research
Immunology, Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:1000-1:4000; IP: 1:500-1:1000; IHC: 1:20-1:200; IF: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
35 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC, FC, IF, IP
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