PLK4 antibody
Product Specifications
Background
This gene encodes a member of the polo family of serine/threonine protein kinases. The protein localizes to centrioles, complex microtubule-based structures found in centrosomes, and regulates centriole duplication during the cell cycle. Three alternatively spliced transcript variants that encode different protein isoforms have been found for this gene.
Synonyms
Serine/threonine-protein kinase PLK4|Polo-like kinase 4 (PLK-4)|Serine/threonine-protein kinase 18|Serine/threonine-protein kinase Sak|PLK4|SAK|STK18
Gene ID
10733
UniProt
O00444
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
polo-like kinase 4 (Drosophila)
Target
PLK4
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Field of Research
Metabolism, Developmental biology
Purification
Immunogen affinity purified
Dilution
WB: 1:200 - 1:2000; IHC: 1:50 - 1:100
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
115 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
CAS Number
9007-83-4
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