PLCD3 antibody
Product Specifications
Background
Hydrolyzes the phosphatidylinositol 4,5-bisphosphate (PIP2) to generate 2 second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) . DAG mediates the activation of protein kinase C (PKC), while IP3 releases Ca (2+) from intracellular stores. Essential for trophoblast and placental development. May participate in cytokinesis by hydrolyzing PIP2 at the cleavage furrow.
Synonyms
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3|Phosphoinositide phospholipase C-delta-3|Phospholipase C-delta-3 (PLC-delta-3) |PLCD3|KIAA1964
Gene ID
113026
UniProt
Q8N3E9
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Phospholipase C, delta 3
Target
PLCD3
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB
Field of Research
Signal Transduction, Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
85 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB
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