PKD2L1 antibody
Product Specifications
Background
Pore-forming subunit of a ciliary calcium channel that controls calcium concentration within primary cilia without affecting cytoplasmic calcium concentration. Forms a heterodimer with PKD1L1 in primary cilia and forms a calcium-permeant ciliary channel that regulates sonic hedgehog/SHH signaling and GLI2 transcription. May act as a sour taste receptor by forming a calcium channel with PKD1L3 in gustatory cells; however, its contribution to sour taste perception is unclear in vivo and may be indirect.
Synonyms
Polycystin-2-like protein 1 (Polycystin-2L1)|Polycystic kidney disease 2-like 1 protein|Polycystin-2 homolog|Polycystin-L|Polycystin-L1|PKD2L1|PKD2L|PKDL|TRPP3
Gene ID
9033
UniProt
Q9P0L9
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
polycystic kidney disease 2-like 1
Target
PKD2L1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB
Field of Research
Signal Transduction, Developmental biology
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
92 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)
CAS Number
9007-83-4
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