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PIP4K2A antibody

Product Specifications

Background

Phosphatidylinositol-5, 4-bisphosphate, the precursor to second messengers of the phosphoinositide signal transduction pathways, is thought to be involved in the regulation of secretion, cell proliferation, differentiation, and motility. The protein encoded by this gene is one of a family of enzymes capable of catalyzing the phosphorylation of phosphatidylinositol-5-phosphate on the fourth hydroxyl of the myo-inositol ring to form phosphatidylinositol-5, 4-bisphosphate. The amino acid sequence of this enzyme does not show homology to other kinases, but the recombinant protein does exhibit kinase activity. This gene is a member of the phosphatidylinositol-5-phosphate 4-kinase family.

Synonyms

Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha|1-phosphatidylinositol 5-phosphate 4-kinase 2-alpha|Diphosphoinositide kinase 2-alpha|PIP5KIII|Phosphatidylinositol 5-Phosphate 4-Kinase (PI5P4Kalpha)|Phosphatidylinositol 5-phosphate 4-kinase type II alpha (PI(5)P 4-kinase type II alpha, PIP4KII-alpha)|PtdIns(4)P-5-kinase B isoform|PtdIns(4)P-5-kinase C isoform|PtdIns(5)P-4-kinase isoform 2-alpha|PIP4K2A|PI5P4KA|PIP5K2|PIP5K2A

Gene ID

5305

UniProt

P48426

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

phosphatidylinositol-5-phosphate 4-kinase, type II, alpha

Target

PIP4K2A

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, WB, IHC, IF

Field of Research

Signal Transduction, Metabolism

Purification

Immunogen affinity purified

Dilution

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Molecular Weight

46 kDa

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

CAS Number

9007-83-4

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