Alpidem

Alpidem selectively binds to α1β2γ2 subunit-containing GABAA receptor with an IC50 of 17 nM and exerts anxiolytic effect[1].

Product Specifications

CAS Number

[82626-01-5]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

GABA Receptor

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/alpidem.html

Purity

99.70

Solubility

DMSO : 25 mg/mL (ultrasonic)

Smiles

O=C(N(CCC)CCC)CC1=C(C2=CC=C(Cl)C=C2)N=C3C=CC(Cl)=CN31

Molecular Formula

C21H23Cl2N3O

Molecular Weight

404.34

Precautions

H302, H315, H319, H335

References & Citations

[1]Faure-Halley C, et al. Expression and properties of recombinant alpha 1 beta 2 gamma 2 and alpha 5 beta 2 gamma 2 forms of the rat GABAA receptor. Eur J Pharmacol. 1993 Aug 15;246 (3) :283-7.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

Launched

Available Sizes

Curated Selection

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