Alpidem
Product Specifications
UNSPSC Description
Alpidem selectively binds to α1β2γ2 subunit-containing GABAA receptor with an IC50 of 17 nM and exerts anxiolytic effect[1].
Target Antigen
GABA Receptor
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel;Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/alpidem.html
Purity
99.49
Solubility
DMSO : 25 mg/mL (ultrasonic)
Smiles
O=C(N(CCC)CCC)CC1=C(C2=CC=C(Cl)C=C2)N=C3C=CC(Cl)=CN31
Molecular Weight
404.34
References & Citations
[1]Faure-Halley C, et al. Expression and properties of recombinant alpha 1 beta 2 gamma 2 and alpha 5 beta 2 gamma 2 forms of the rat GABAA receptor. Eur J Pharmacol. 1993 Aug 15;246(3):283-7.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-W013150/Alpidem-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-W013150/Alpidem-SDS-MedChemExpress.pdf
Clinical Information
Launched
CAS Number
82626-01-5
Available Sizes
Curated Selection
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