PI4K2B antibody
Product Specifications
Background
Together with PI4K2A and the type III PI4Ks(PIK4CA and PIK4CB) it contributes to the overall PI4-kinase activity of the cell. This contribution may be especially significant in plasma membrane, endosomal and Golgi compartments. The phosphorylation of phosphatidylinositol(PI) to PI4P is the first committed step in the generation of phosphatidylinositol 4,5-bisphosphate(PIP2), a precursor of the second messenger inositol 1,4,5-trisphosphate(InsP3). Contributes to the production of InsP3 in stimulated cells and is likely to be involved in the regulation of vesicular trafficking.
Synonyms
Phosphatidylinositol 4-kinase type 2-beta|Phosphatidylinositol 4-kinase type II-beta (PI4KII-BETA)|PI4K2B
Gene ID
55300
UniProt
Q8TCG2
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
phosphatidylinositol 4-kinase type 2 beta
Target
PI4K2B
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC, IF
Field of Research
Signal Transduction, Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
50-54 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)
CAS Number
9007-83-4
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