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PHF20 antibody

Product Specifications

Background

Methyllysine-binding protein, component of the MOF histone acetyltransferase protein complex. Not required for maintaining the global histone H4 'Lys-16' acetylation (H4K16ac) levels or locus specific histone acetylation, but instead works downstream in transcriptional regulation of MOF target genes (By similarity) . As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues. Contributes to methyllysine-dependent p53/TP53 stabilization and up-regulation after DNA damage.

Synonyms

PHD finger protein 20|Glioma-expressed antigen 2|Hepatocellular carcinoma-associated antigen 58|Novel zinc finger protein|Transcription factor TZP|PHF20|C20orf104|GLEA2|HCA58|NZF|TZP

Gene ID

51230

UniProt

Q9BVI0

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

PHD finger protein 20

Target

PHF20

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, WB

Field of Research

Epigenetics, Metabolism

Purification

Immunogen affinity purified

Dilution

WB: 1:500-1:2000

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Molecular Weight

130 kDa

Shipping Conditions

4°C with ice bag

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Tested Applications

ELISA, WB

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