PHC2 antibody
Product Specifications
Background
Component of a Polycomb group(PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.
Synonyms
Polyhomeotic-like protein 2 (hPH2)|Early development regulatory protein 2|PHC2|EDR2|PH2
Gene ID
1912
UniProt
Q8IXK0
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
polyhomeotic homolog 2(Drosophila)
Target
PHC2
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB,IF
Field of Research
Metabolism, Developmental biology
Purification
Immunogen affinity purified
Dilution
WB: 1:200-1:2000; IF: 1:50-1:500
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
40 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)
CAS Number
9007-83-4
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