PHC2 antibody
Product Specifications
Background
Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.
Synonyms
Polyhomeotic-like protein 2 (hPH2) |Early development regulatory protein 2|PHC2|EDR2|PH2
Gene ID
1912
UniProt
Q8IXK0
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Polyhomeotic homolog 2 (Drosophila)
Target
PHC2
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB,IF
Field of Research
Metabolism, Developmental biology
Purification
Immunogen affinity purified
Dilution
WB: 1:200-1:2000; IF: 1:50-1:500
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
40 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IF
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