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CDK14 antibody

Product Specifications

Background

PFTK1 is a Cdc2-related protein kinase, also named as PFTAIRE1, CDK14 and belongs to the CMGC Ser/Thr protein kinase family and CDC2/CDKX subfamily. It acts as a cyclin-dependent kinases that regulates cell cycle progression and cell proliferation. The PFTK1 protein shows high homology with mouse Pftaire1, a Cdc2-related protein expressed primarily in the postnatal and adult nervous system (PMID:9202329) . The protein contains 2 predicted nuclear localization signals that the N-terminal nuclear localization signals do not play a role in vivo (PMID:11313143) . It has 3 isoforms produced by alternative splicing. This antibody is specific to PFTK1.

Synonyms

Cyclin-dependent kinase 14|Cell division protein kinase 14|Serine/threonine-protein kinase PFTAIRE-1 (hPFTAIRE1) |CDK14|KIAA0834|PFTK1

UniProt

O94921

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

PFTAIRE protein kinase 1

Target

CDK14

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, WB, IHC

Field of Research

Cell Division and Proliferation, Metabolism

Purification

Immunogen affinity purified

Dilution

WB: 1:500-1:5000; IHC: 1:50-1:500

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Molecular Weight

48-53 kDa

Shipping Conditions

4°C with ice bag

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Tested Applications

ELISA, WB, IHC

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