PDE3B antibody
Product Specifications
Background
Cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. May play a role in fat metabolism. Regulates cAMP binding of RAPGEF3. Through simultaneous binding to RAPGEF3 and PIK3R6 assembles a signaling complex in which the PI3K gamma complex is activated by RAPGEF3 and which is involved in angiogenesis.
Synonyms
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3B|CGIPDE1 (CGIP1)|Cyclic GMP-inhibited phosphodiesterase B (CGI-PDE B)|PDE3B
Gene ID
5140
UniProt
Q13370
Host
Rabbit
Reactivity
Human
Immunogen
phosphodiesterase 3B, cGMP-inhibited
Target
PDE3B
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, IP
Field of Research
Signal Transduction, Metabolism
Purification
Immunogen affinity purified
Dilution
IP: 1:200-1:2000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
124 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)
CAS Number
9007-83-4
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