PCMT1 antibody
Product Specifications
Background
Catalyzes the methyl esterification of L-isoaspartyl and D-aspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins. Acts on EIF4EBP2, microtubule-associated protein 2, calreticulin, clathrin light chains a and b, Ubiquitin carboxyl-terminal hydrolase isozyme L1, phosphatidylethanolamine-binding protein 1, stathmin, beta-synuclein and alpha-synuclein.
Synonyms
Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PIMT)|L-isoaspartyl protein carboxyl methyltransferase|Protein L-isoaspartyl/D-aspartyl methyltransferase|Protein-beta-aspartate methyltransferase|PCMT1
Gene ID
5110
UniProt
P22061
Host
Mouse
Reactivity
Human
Immunogen
protein-L-isoaspartate(D-aspartate) O-methyltransferase
Target
PCMT1
Clonality
Monoclonal
Isotype
IgG1
Clone
7G6
Applications
ELISA, WB, IF
Field of Research
Metabolism
Purification
Protein A+G purification
Dilution
WB: 1:500-1:2000; IF: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
25 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)
CAS Number
9007-83-4
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