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PCMT1 antibody

Product Specifications

Background

Catalyzes the methyl esterification of L-isoaspartyl and D-aspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins. Acts on EIF4EBP2, microtubule-associated protein 2, calreticulin, clathrin light chains a and b, Ubiquitin carboxyl-terminal hydrolase isozyme L1, phosphatidylethanolamine-binding protein 1, stathmin, beta-synuclein and alpha-synuclein.

Synonyms

Protein-L-isoaspartate (D-aspartate) O-methyltransferase (PIMT) |L-isoaspartyl protein carboxyl methyltransferase|Protein L-isoaspartyl/D-aspartyl methyltransferase|Protein-beta-aspartate methyltransferase|PCMT1

Gene ID

5110

UniProt

P22061

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Protein-L-isoaspartate (D-aspartate) O-methyltransferase

Target

PCMT1

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, WB, IHC

Field of Research

Metabolism

Purification

Immunogen affinity purified

Dilution

WB: 1:500-1:2000; IHC: 1:20-1:200

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Molecular Weight

25-28 kDa

Shipping Conditions

4°C with ice bag

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Tested Applications

ELISA, WB, IHC

Frequently Asked Questions

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