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PCBD1 antibody

Product Specifications

Background

Involved in tetrahydrobiopterin biosynthesis. Seems to both prevent the formation of 7-pterins and accelerate the formation of quinonoid-BH2. Coactivator for HNF1A-dependent transcription. Regulates the dimerization of homeodomain protein HNF1A and enhances its transcriptional activity.

Synonyms

Pterin-4-alpha-carbinolamine dehydratase (PHS) |4-alpha-hydroxy-tetrahydropterin dehydratase|Dimerization cofactor of hepatocyte nuclear factor 1-alpha (DCoH, Dimerization cofactor of HNF1) |Phenylalanine hydroxylase-stimulating protein|Pterin carbinolamine dehydratase (PCD) |PCBD1|DCOH|PCBD

Gene ID

5092

UniProt

P61457

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha

Target

PCBD1

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, WB, IHC, IF

Field of Research

Metabolism

Purification

Immunogen affinity purified

Dilution

WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Molecular Weight

12 kDa

Shipping Conditions

4°C with ice bag

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Tested Applications

ELISA, WB, IHC, IF

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