PBK antibody
Product Specifications
Background
Phosphorylates MAP kinase p38. Seems to be active only in mitosis. May also play a role in the activation of lymphoid cells. When phosphorylated, forms a complex with TP53, leading to TP53 destabilization and attenuation of G2/M checkpoint during doxorubicin-induced DNA damage.
Synonyms
Lymphokine-activated killer T-cell-originated protein kinase|Cancer/testis antigen 84 (CT84)|MAPKK-like protein kinase|Nori-3|PDZ-binding kinase|Spermatogenesis-related protein kinase (SPK)|T-LAK cell-originated protein kinase|PBK|TOPK
Gene ID
55872
UniProt
Q96KB5
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
PDZ binding kinase
Target
PBK
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC, IF, FC
Field of Research
Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
36-40 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)
CAS Number
9007-83-4
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