PAX6 antibody
Product Specifications
Background
Transcription factor with important functions in the development of the eye, nose, central nervous system and pancreas. Required for the differentiation of pancreatic islet alpha cells(By similarity). Competes with PAX4 in binding to a common element in the glucagon, insulin and somatostatin promoters. Regulates specification of the ventral neuron subtypes by establishing the correct progenitor domains(By similarity). Isoform 5a appears to function as a molecular switch that specifies target genes.
Synonyms
Paired box protein Pax-6|Aniridia type II protein|Oculorhombin|PAX6|AN2
Gene ID
5080
UniProt
P26367
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
paired box 6
Target
PAX6
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, IHC, WB
Field of Research
Neuroscience, Stem Cells, Metabolism, Developmental biology
Purification
Immunogen affinity purified
Dilution
WB: 1:300-1:1200; IHC: 1:50-1:500; IF: 1:50-1:500
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
47 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)
CAS Number
9007-83-4
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