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PARP2 antibody

Product Specifications

Background

Involved in the base excision repair(BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks.

Synonyms

Poly [ADP-ribose] polymerase 2 (PARP-2, hPARP-2)|ADP-ribosyltransferase diphtheria toxin-like 2 (ARTD2)|DNA ADP-ribosyltransferase PARP2|NAD(+) ADP-ribosyltransferase 2 (ADPRT-2)|Poly[ADP-ribose] synthase 2 (pADPRT-2)|Protein poly-ADP-ribosyltransferase PARP2|PARP2|ADPRT2|ADPRTL2

Gene ID

10038

UniProt

Q9UGN5

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

poly(ADP-ribose) polymerase 2

Target

PARP2

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, WB

Field of Research

Metabolism

Purification

Immunogen affinity purified

Dilution

WB: 1:500-1:2000

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Molecular Weight

66 kDa

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)

CAS Number

9007-83-4

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