PARD6B antibody
Product Specifications
Background
Adapter protein involved in asymmetrical cell division and cell polarization processes. Probably involved in formation of epithelial tight junctions. Association with PARD3 may prevent the interaction of PARD3 with F11R/JAM1, thereby preventing tight junction assembly. The PARD6-PARD3 complex links GTP-bound Rho small GTPases to atypical protein kinase C proteins.
Synonyms
Partitioning defective 6 homolog beta (PAR-6 beta, PAR-6B)|PARD6B|PAR6B
Gene ID
84612
UniProt
Q9BYG5
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
par-6 partitioning defective 6 homolog beta(C. elegans)
Target
PARD6B
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC, IF, IP, FC
Field of Research
Signal Transduction, Developmental biology
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200; IF: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
50-53 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)
CAS Number
9007-83-4
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