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PAPSS2 antibody

Product Specifications

Background

Bifunctional enzyme with both ATP sulfurylase and APS kinase activity, which mediates two steps in the sulfate activation pathway. The first step is the transfer of a sulfate group to ATP to yield adenosine 5'-phosphosulfate (APS), and the second step is the transfer of a phosphate group from ATP to APS yielding 3'-phosphoadenylylsulfate (PAPS: activated sulfate donor used by sulfotransferase) . In mammals, PAPS is the sole source of sulfate; APS appears to be only an intermediate in the sulfate-activation pathway. May have a important role in skeletogenesis during postnatal growth (By similarity) .

Synonyms

Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2 (PAPS synthase 2, PAPSS 2) |Sulfurylase kinase 2 (SK 2, SK2) |PAPSS2|ATPSK2

Gene ID

9060

UniProt

O95340

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

3'-phosphoadenosine 5'-phosphosulfate synthase 2

Target

PAPSS2

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, WB

Field of Research

Metabolism

Purification

Immunogen affinity purified

Dilution

WB: 1:500-1:2000

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Molecular Weight

70 kDa

Shipping Conditions

4°C with ice bag

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Tested Applications

ELISA, WB

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