PAK1IP1 antibody
Product Specifications
Background
Negatively regulates the PAK1 kinase. PAK1 is a member of the PAK kinase family, which have been shown to play a positive role in the regulation of signaling pathways involving MAPK8 and RELA. PAK1 exists as an inactive homodimer, which is activated by binding of small GTPases such as CDC42 to an N-terminal regulatory domain. PAK1IP1 also binds to the N-terminus of PAK1, and inhibits the specific activation of PAK1 by CDC42.
Synonyms
p21-activated protein kinase-interacting protein 1|PAK/PLC-interacting protein 1 (hPIP1)|PAK1-interacting protein 1|WD repeat-containing protein 84|PAK1IP1|PIP1|WDR84
Gene ID
55003
UniProt
Q9NWT1
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
PAK1 interacting protein 1
Target
PAK1IP1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB
Field of Research
Signal Transduction
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
44 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)
CAS Number
9007-83-4
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