PAIP1 antibody
Product Specifications
Background
Acts as a coactivator in the regulation of translation initiation of poly(A)-containing mRNAs. Its stimulatory activity on translation is mediated via its action on PABPC1. Competes with PAIP2 for binding to PABPC1. Its association with EIF4A and PABPC1 may potentiate contacts between mRNA termini. May also be involved in translationally coupled mRNA turnover. Implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability(mCRD) domain.
Synonyms
Polyadenylate-binding protein-interacting protein 1 (PABP-interacting protein 1, PAIP-1, Poly(A)-binding protein-interacting protein 1)|PAIP1
Gene ID
10605
UniProt
Q9H074
Host
Rabbit
Reactivity
Human, Mouse, Rat, Monkey
Immunogen
poly(A) binding protein interacting protein 1
Target
PAIP1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IF
Field of Research
Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IF: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
60 kDa, 51 kDa, 40 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)
CAS Number
9007-83-4
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