PACSIN3 antibody
Product Specifications
Background
Plays a role in endocytosis and regulates internalization of plasma membrane proteins. Overexpression impairs internalization of SLC2A1/GLUT1 and TRPV4 and increases the levels of SLC2A1/GLUT1 and TRPV4 at the cell membrane. Inhibits the TRPV4 calcium channel activity (By similarity) .
Synonyms
Protein kinase C and casein kinase substrate in neurons protein 3|SH3 domain-containing protein 6511|PACSIN3
Gene ID
29763
UniProt
Q9UKS6
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Protein kinase C and casein kinase substrate in neurons 3
Target
PACSIN3
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC, FC, IF
Field of Research
Neuroscience, Signal Transduction, Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
48 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC, FC, IF
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