TP63 antibody
Product Specifications
Background
TP63, also named KET, P63, P73H, P73L and TP73L, belongs to the p53 family. It is a homologue of the tumor suppressor p53 and p73 genes. It is involved in malignancy acquisition and maintenance of cells. Unlike p53, the p63 gene encodes multiple isotypes with remarkably divergent abilities to transactivate p53 reporter genes and induce apoptosis. TP63 acts as a sequence specific DNA binding transcriptional activator or repressor. TP63 has 12 isoforms with MW 40kd (P40), 50kd (P60),63kd (P63) and 73kd (P73L) . It is Nuclear stain.
Synonyms
Tumor protein 63 (p63) |Chronic ulcerative stomatitis protein (CUSP) |Keratinocyte transcription factor KET|Transformation-related protein 63 (TP63) |Tumor protein p73-like (p73L) |p40|p51|TP63|KET|P63|P73H|P73L|TP73L
Gene ID
8626
UniProt
Q9H3D4
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Tumor protein p63
Target
TP63
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC, IF
Field of Research
Metabolism, Immunology, Cancer, Stem Cells, Cell Division and Proliferation
Purification
Immunogen affinity purified
Dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:20 - 1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
45-75 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC, IF
Immunogen Sequence
421-680aa
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