CTNND1 antibody
Product Specifications
Background
Binds to and inhibits the transcriptional repressor ZBTB33, which may lead to activation of target genes of the Wnt signaling pathway (By similarity) . Associates with and regulates the cell adhesion properties of both C-, E-and N-cadherins, being critical for their surface stability. Implicated both in cell transformation by SRC and in ligand-induced receptor signaling through the EGF, PDGF, CSF-1 and ERBB2 receptors. Promotes GLIS2 C-terminal cleavage.
Synonyms
Catenin delta-1|Cadherin-associated Src substrate (CAS) |p120 catenin (p120 (ctn) ) |p120 (cas) |CTNND1|KIAA0384
UniProt
O60716
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Catenin, delta 1
Target
CTNND1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IF, IP,IHC
Field of Research
Cancer, Immunology, Signal Transduction, Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:1000; IP: 1:500-1:1000; IHC: 1:50-1:500; IF: 1:10-1:100
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
105 kDa, 66 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IF, IP, IHC
Immunogen Sequence
470-712aa
Curated Selection
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