OSGEP antibody
Product Specifications
Background
Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t (6) A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. OSGEP likely plays a direct catalytic role in this reaction, but requires other protein (s) of the complex to fulfill this activity.
Synonyms
TRNA N6-adenosine threonylcarbamoyltransferase|N6-L-threonylcarbamoyladenine synthase (t (6) A synthase) |O-sialoglycoprotein endopeptidase (hOSGEP) |t (6) A37 threonylcarbamoyladenosine biosynthesis protein OSGEP|tRNA threonylcarbamoyladenosine biosynthesis protein OSGEP|OSGEP|GCPL1
Gene ID
55644
UniProt
Q9NPF4
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
O-sialoglycoprotein endopeptidase
Target
OSGEP
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC, IF
Field of Research
Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
36 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC, IF
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