ORAI1 antibody
Product Specifications
Background
Ca (2+) release-activated Ca (2+) (CRAC) channel subunit which mediates Ca (2+) influx following depletion of intracellular Ca (2+) stores and channel activation by the Ca (2+) sensor, STIM1. CRAC channels are the main pathway for Ca (2+) influx in T-cells and promote the immune response to pathogens by activating the transcription factor NFAT (PubMed:16582901) .
Synonyms
Calcium release-activated calcium channel protein 1|Protein orai-1|Transmembrane protein 142A|ORAI1|CRACM1|TMEM142A
Gene ID
84876
UniProt
Q96D31
Host
Mouse
Reactivity
Human
Immunogen
ORAI calcium release-activated calcium modulator 1
Target
ORAI1
Clonality
Monoclonal
Isotype
IgG1
Applications
ELISA, WB,IHC
Field of Research
Immunology, Signal Transduction
Purification
Protein A+G purification
Dilution
WB: 1:500-1:2000; IHC: 1:50-1:500
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
32 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Clone ID
8C0
Tested Applications
ELISA, WB, IHC
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
ICH1165UL-5mg 5 mg
Anti-Mouse CD318 (9a2) In Vivo Antibody - Ultra-Low Endotoxin
Sign In for Pricing
View Details CSB-EP649669PI-01 20 µg
Recombinant Pig Scavenger receptor cysteine-rich type 1 protein M130 (CD163), partial
Sign In for Pricing
View Details CSB-EP649669PI-02 100 µg
Recombinant Pig Scavenger receptor cysteine-rich type 1 protein M130 (CD163), partial
Sign In for Pricing
View Details CSB-EP649669PI-03 1 mg
Recombinant Pig Scavenger receptor cysteine-rich type 1 protein M130 (CD163), partial
Sign In for Pricing
View Details 