ORAI1 antibody
Product Specifications
Background
Ca (2+) release-activated Ca (2+) (CRAC) channel subunit which mediates Ca (2+) influx following depletion of intracellular Ca (2+) stores and channel activation by the Ca (2+) sensor, STIM1. CRAC channels are the main pathway for Ca (2+) influx in T-cells and promote the immune response to pathogens by activating the transcription factor NFAT (PubMed:16582901) .
Synonyms
Calcium release-activated calcium channel protein 1|Protein orai-1|Transmembrane protein 142A|ORAI1|CRACM1|TMEM142A
Gene ID
84876
UniProt
Q96D31
Host
Rabbit
Reactivity
Human, Mouse, Rat, Zebrafish
Immunogen
ORAI calcium release-activated calcium modulator 1
Target
ORAI1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IF
Field of Research
Immunology, Signal Transduction
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:1000; IF: 1:10-1:100
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
45 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IF
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