OLR1 antibody
Product Specifications
Background
This gene encodes a low density lipoprotein receptor that belongs to the C-type lectin superfamily. This gene is regulated through the cyclic AMP signaling pathway. The encoded protein binds, internalizes and degrades oxidized low-density lipoprotein. This protein may be involved in the regulation of Fas-induced apoptosis. This protein may play a role as a scavenger receptor. Mutations of this gene have been associated with atherosclerosis, risk of myocardial infarction, and may modify the risk of Alzheimer's disease. Alternate splicing results in multiple transcript variants.
Synonyms
Oxidized low-density lipoprotein receptor 1 (Ox-LDL receptor 1) |C-type lectin domain family 8 member A|Lectin-like oxidized LDL receptor 1 (LOX-1, Lectin-like oxLDL receptor 1, hLOX-1) |Lectin-type oxidized LDL receptor 1|Oxidized low-density lipoprotein receptor 1, soluble form|OLR1|CLEC8A|LOX1
Gene ID
4973
UniProt
P78380
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Oxidized low density lipoprotein (lectin-like) receptor 1
Target
OLR1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Field of Research
Immunology, Cardiovascular, Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
26 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC
More Discoveries
Explore Other Products
Browse additional items from our catalog
